麦可(狄恩肯恩饰)在路上搭载了年轻性感的正妹(克莉丝汀波森饰)，麦可原先认为漫漫公路有正妹相伴艳福不浅，自以为遇上了豔遇的他，却不知道自己即将陷入一连串的阴谋及杀机，一趟没有终点的旅程即将展开…故事描述一个男人在路途中载了一位年轻的女人，原来只是好心借人搭便车，结果男主人公却发现自己陷入了一场可怕的午夜梦魇……Ifshelookstoogoodtobetrue,thensheabsolutelyis.JustaskMichaelAnderson(DeanCain),agulliblefilmeditorwhopicksupasexyyounghitchhiker(ChristieBurson)intheArizonadesert.Afterthemostthrillingonenightstandofhislife,Michaelbecomesembroiledinatwistedloveconinvolvingasadisticcrimeboss(MichaelMadsen),alonelyhenchman,andathievingbankmanager.Trustisn’tjustabitch,it’sadirtylittletrick!Acrimebosssmoneyismissingandhewantsitbackbyanyaymeans.Thebeautifulhitchhikerhasitandwantstomakethegetaway.Alexander"Sasha"Shulginisthescientistbehindmorethan200psychedeliccompounds-includingMDMA,morecommonlyknownasEcstasy.Consideredtobeoneofthegreatestchemistsofthe20thcentury,Sasha’svastarrayofdiscoverieshavehadaprofoundimpactinthefieldofpsychedelicresearch,makinghimasubjectoffascinationandcontroversyamongfellowscientistsandafolkherotorecreationalusersofpsychedelics.DirtyPicturesuncoversthelifeworkofDr.ShulginandtakesviewersinsidehisNorthernCaliforniahomewhereheliveswithhiswifeof40yearsandcontinuestocarryoutexperimentsinamakeshiftlaboratory.DirectorétienneSauretlikewisedelvesintothebroaderworldofpsychedelicresearch-wherethefieldsofchemistry,neuroscienceandphilosophyintersect-andinvestigateswhetherornotthisparticularfieldcouldaidinsolvingthedeepestmysteriesofthehumanmind.
